What happens when human growth hormone (HGH) levels are too low?

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Growth hormone deficiency affects adults and children differently.

HGH deficiency in adults​

When adults have a lack of HGH, it causes the following issues:

• Reduced sense of well-being.
• Increased body fat.
• Increased risk of heart disease.
• Weak heart, muscles and bones.

In adults, hypopituitarism that results in HGH deficiency may develop due to a benign pituitary adenoma (a noncancerous tumor) or damage to your pituitary gland or hypothalamus.

HGH deficiency in children​

A lack of HGH in children results in poor growth. The main sign of HGH deficiency in children is slow height growth each year after a child’s third birthday. This means they grow less than about 1.4 inches in height a year. A child with HGH deficiency may also have:

• A younger-looking face than what’s expected for their age.
• Impaired hair growth.
• Delayed puberty.

In children, hypopituitarism that results in HGH deficiency may be present from birth where the cause can be unknown (idiopathic), genetic or due to injury to their pituitary gland (during fetal development or at birth).

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